Journals Publishing Trial Protocols

either as part of a protocol or as a stand-alone document. Many journals now publish trial protocols and some publish statistical analysis plans as stand-alone documents. The statistical analysis plan.

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Registered trials were also significantly more likely than unregistered trials to be subsequently published with the same primary outcomes as defined in the protocol (64 percent. and the limited.

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Trial protocols are needed for a proper assessment of the veracity of drug trial reports. The researchers found widespread redactions in the protocols for commercially sponsored trials. New research.

Interview with Dr. Jeffrey Drazen on the Journal’s data-analysis challenge. data generated by interventional clinical trials because trial participants have put themselves at risk. In January 2016.

Objective: To examine the effects of different sit-stand protocols on work-time sitting and physical activity (PA) of office workers. Methods: Participants (n = 26, 77% women, mean age 42) were.

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As a pragmatic trial. the benefits from the protocol would have been even more positive for the intervention." About the Journal The Journal of Alternative and Complementary Medicine (JACM) is a.

An analysis of more than 100 clinical trials found that they were often unregistered, unpublished and. and 57 percent were published. A primary outcome was not defined in 20 percent. Discrepancies.

In 2004 the International Committee of Medical Journal Editors (ICMJE) announced that clinical trials commencing after 1 July 2005 would be subject to a new trial registration policy. In order to be.

A new analysis published in the British Journal of Clinical Pharmacology indicates that ‘first-in-man’ clinical trial protocols in the Netherlands often lack a consistent consideration of.

A major medical journal has updated its instructions to authors, now requiring that they publish protocols of clinical trials, along with any changes made along the way. This change was something we.

A meta-analysis, published online in the Journal of the American Heart Association December. "As such, it raises the need to consider whether changes to the trial protocol and patient information.

and Ben Goldacre’s COMPARE project recently found that of 67 trials published by the most prestigious medical journals, 58 covertly altered their outcome measures from the registered protocol. This.

A new analysis published in the British Journal of Clinical Pharmacology indicates that ‘first-in-man’ clinical trial protocols in the Netherlands often lack a consistent consideration of.

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can prevent future MRSA infections by following a standard bathing protocol after discharge, according to research results published in the February 14 issue of the New England Journal of Medicine.

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Carlisle analyzed data from a total of 5087 trials published in various journals. These included 934 studies published. review of their data and randomization procedures identified protocol.

In addition, if peer review of the published literature and protocol is necessary, these reports could ensure that researchers stick to the trial protocols they originally registered. BMC Medicine.

Study protocols provide a detailed blueprint for upcoming clinical trials and Medicine® believes publishing registered trials will help improve the standard of medical research. Study protocols enable.